Current focus of our research group is development and standardization of animal models of metabolic syndrome: type II diabetes, wound healing sepsis, cancer, iron deficiency anaemia, neurodegenerative diseases and testing of novel targets, natural products, probiotics and their metabolites for their therapeutic activities in in-vitro and in-vivo systems. Our lab has done extensive studies to establish therapeutic role of gelsolin, probiotics and their secondary metabolites in inflammation, diabetes, wound healing etc. Besides this, we are also interested to study safety and efficacy of new chemical entities and small peptides against cancer, antifungal and neurodegenerative diseases (Parkinson and Alzheimer diseases). We welcome students/research fellows who are interested in learning and contributing to the advancement in these areas to join our group in IMTECH.

• Dubey AK, Podia M, Priyanka, Raut S, Singh S, Pinnaka AK, Khatri N. (2021). Insight Into the Beneficial Role of Lactiplantibacillus plantarum Supernatant Against Bacterial Infections, Oxidative Stress, and Wound Healing in A549 Cells and BALB/c Mice. Front Pharmacol. 2021 Nov 4;12:728614. doi: 10.3389/fphar.2021.728614. eCollection 2021.PMID: 34803678.
• Bharti R, Chopra BS, Raut S, Khatri N. (2021). Pueraria tuberosa: A Review on Traditional Uses, Pharmacology, and Phytochemistry. Front Pharmacol. 2021 Jan 27;11:582506. doi: 10.3389/fphar.2020.582506. eCollection 2020.PMID: 33708108.
• Akhtar MN, Mishra M, Yadav V, Yadav M, Gujar R, Lal S, Kumar R, Khatri N, Sen P. (2020).  Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells. .PLoS Pathog. 2020 Dec 28;16(12):e1009136. doi: 10.1371/journal.ppat.1009136. eCollection 2020 Dec.PMID: 33370418.
• Vaid B, Chopra BS, Raut S, Sagar A, Badmalia MD, Ashish, Khatri N. (2020).  Antioxidant and Wound Healing Property of Gelsolin in 3T3-L1 Cells. Oxid Med Cell Longev. 2020 Feb 12;2020:4045365. doi: 10.1155/2020/4045365. eCollection 2020.PMID: 32104532.
• Saini A, Mahajan S, Bhagyaraj E, Kalra R, Nanduri R, Gupta R, Khatri N, Gupta P. (2020).  An Accord of Nuclear Receptor Expression in CD4+ T Cells in Rheumatoid Arthritis. Immuno horizons. 2019 Aug 22;3(8):402-411. doi: 10.4049/immunohorizons.1900043.PMID: 31439624.
• Gupta AK, Chopra BS, Vaid B, Sagar A, Raut S, Badmalia MD, Ashish, Khatri N. (2019).  Protective effects of gelsolin in acute pulmonary thromboembolism and thrombosis in the carotid artery of mice. PLoS One. 2019 Apr 19;14(4):e0215717. doi: 10.1371/journal.pone.0215717. eCollection 2019.PMID: 31002695.

Lab Members